Our clinical research activities focus on the development of new diagnostic and therapeutic applications intended to optimize the treatment of diseases of the musculoskeletal system of the hand. In clinical studies, we compare conservative as well as surgical strategies and evaluate critical factors such as pain, healing performance and revision rate. Examples are investigations on the treatment of rheumatoid arthritis (in collaboration with the Department of Rheumatology), the treatment of Morbus Dupuytren (in collaboration with the Department of Handtherapy) and the adaptation of treatment schemes after injuries of the flexor tendon. Furthermore, we analyze the benefit of sonographical investigations within Tendovaginitis stenosans, the application of new drugs such as Xiapex and the use of nerve allotransplantation in injured nerves. The aim of all measures is supporting rehabilitation and restoration of mobility as well as affective sensation. In various mid- and long-term clinical studies, we evaluate the efficacy of our diagnostic and therapeutic approaches.
Another focus is laying on the development of new immunological therapy concepts reducing or even eliminating critical rejection processes after transplantation. For this purpose, different innovative drug delivery systems such as the application of new hydrogels are currently under evaluation. Loaded with immunosuppressive drugs, the local release is intended to significantly reduce systemic side effects being observed in current treatment schemes. International collaborations enable us to perform experimental research on severed limbs. Perfusion studies, performed on isolated animal limbs will generate new scientific knowledge and will optimize future clinical preservation strategies of severed tissue.
All current projects and references are listed on our homepage.
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